High Purity Medical Grade Nicotinamide Powder

Product Information

Niacinamide: Nicotinamide belongs to the pyridine Intermediates of Pharmaceutical Intermediates. It is a compound containing a pyridine ring and an amide group. It is a form of vitamin B3 and is widely used in the pharmaceutical and nutraceutical industries.

Nicotinamide, also known as nicotinamide, is an amide compound of nicotinic acid. White crystalline powder; odorless or almost odorless, bitter taste; slightly hygroscopic. Soluble in water or ethanol, soluble in glycerol. It is used clinically to combat pellagra, stomatitis, lingual inflammation, sick sinus node syndrome, and atrioventricular block.

Main sources of niacinamide
It is found in nature mainly in the outer skin of cereals, yeast, peanuts, meat, animal organ offal, milk and green leafy vegetables. It can be synthesized from tryptophan in the body, but with very low efficiency. Niacin can be synthesized by Escherichia coli (Escherichiacoli) and others in the intestines, and then converted to nicotinamide.
Production methods of nicotinamide
(1) β-methyl pyridine is oxidized to nicotinic acid by air, and the latter is produced by the action of ammonium hydroxide and then heated and dehydrated.
(2) the nicotinic acid, boric acid and ammonia into the reaction pot, stirring through the ammonia, temperature dissolution; and then distillation recovery of ammonia to 120 ~ C and then moved to the dehydration pot to continue to concentrate; when the temperature reaches 145 ° C began to add liquid ammonia, and continue to pass the ammonia reaction at 185 ~ 190 ° C for 20 ~ 30 h. Then cooled down to 130 ° C, diluted with distilled water, add activated carbon, and at 70 ~ 80 ~ C After the reaction, filter while hot, the filtrate is cold precipitated in water for 24h, separated and crystallized, and washed with ethanol, dried and finished product, yield 89%.
(3) put nicotinic acid, boric acid and ammonia into the reaction pot, stirring through the ammonia, warming up to dissolve, and then distillate to recover ammonia, to 120 ℃ and then move to the dehydration pot to continue to concentrate when the temperature reaches 145 ℃ to add liquid ammonia, and continue to pass the ammonia reaction at 185-190 ℃ for 20-30h, and then cooled down to 130 ℃, add distilled water to dilute, add activated carbon, and pass the ammonia reaction at 70-80 ℃ Decolorization 2h, after the reaction while hot filtration, filtrate in water cold precipitation for 24h, separation and crystallization, and washed with ethanol, drying the finished product, yield 89%.
(4) It is obtained by salting nicotinic acid with ammonia and then dehydrating it.

Company information

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(1)Water Treatment:The way of water treatment includes physical treatment and chemical treatment. Human water treatment methods have been quite a few years of history, physical methods, including the use of a variety of different pore size of the filter material, the use of adsorption or barrier way, the impurities in the water outside, adsorption method in the more important for the adsorption of activated carbon, barrier method is to pass the water through the filter material, so that the impurities of a larger size can not pass, and thus obtain cleaner water.

(2)Rubber Products are made of rubber raw materials for the rubber mixing machine after refining as raw materials, in the refining of rubber according to the characteristics of the required rubber products and design formulas, and set the required hardness of the product. The products are molded by rubber plate vulcanizing machine. After molding, the products are finally processed with flying edge to make the product surface smooth and burr-free.